Death of Michael Jackson

====Propofol====
[[File:Propofol.jpg|thumb|upright=0.45|alt= An ampoule of propofol |An [[ampoule]] of propofol]]
Of all the drugs found in Jackson's home, the one that most concerned investigators was [[propofol]] (Diprivan), a powerful anesthetic administered intravenously in hospitals to induce and maintain [[anesthesia]] during surgery.<ref name=APJuly3>{{cite news |url=https://www.today.com/popculture/powerful-sedative-found-jackson-s-home-wbna31725355 |title=Powerful sedative found in Michael Jackson's home |agency=Associated Press |work=Today |date=July 3, 2009 |access-date=March 8, 2010 |archive-date=April 11, 2017 |archive-url=https://web.archive.org/web/20170411141226/http://www.today.com/popculture/powerful-sedative-found-jackson-s-home-wbna31725355 |url-status=live }}</ref> Nicknamed "milk of [[amnesia]]" because of its opaque, milk-like appearance (and a [[play on words|play on the words]] "[[milk of magnesia]]"), the drug has been associated with cardiac arrest,<ref name=APJuly3/> but it still may be increasingly [[Off-label use|used off-label]] for [[anxiolytic]] and other medically unsubstantiated purposes.<ref name=GloverJuly4/> Several propofol bottles—both opened and not—were found in his home.<ref name=GloverJuly4>{{cite news |last=Glover |first=Scott |display-authors=etal |url=http://latimesblogs.latimes.com/lanow/2009/07/investigation-into-michael-jacksons-death-looks-at-doctors.html |title=Michael Jackson investigation focuses on doctors |newspaper=Los Angeles Times |date=July 4, 2009 |access-date=July 4, 2009 |archive-date=October 4, 2013 |archive-url=https://web.archive.org/web/20131004232806/http://latimesblogs.latimes.com/lanow/2009/07/investigation-into-michael-jacksons-death-looks-at-doctors.html |url-status=live }}</ref>

On June 30, Cherilyn Lee, a [[nurse practitioner]] who had worked as Jackson's nutritionist, said that he had asked her in May to provide propofol to help him sleep, but she refused. He told her he had been given the drug before for persistent [[insomnia]], and that a doctor had said it was safe as long as he was being monitored. Lee said she received a telephone call from an aide to Jackson on June 21 to say that Jackson was ill, although she no longer worked for him. She reported overhearing Jackson complain that one side of his body was hot, the other side cold. She advised the aide to send Jackson to a hospital; Lee thought she recognized the symptoms, and suspected that Jackson was on propofol.<ref name=Elber>{{cite news |last=Elber |first=Lynn |title=AP Exclusive: Michael Jackson, bedeviled by insomnia, begged for drug, says nurse-nutritionist |agency=Associated Press |date=June 30, 2009}}</ref>{{verify source|reason=Article not available online and AP is not a paper publication – where was it published?|date=February 2022}}

Arnold Klein said that Jackson used an anesthesiologist to administer propofol to help him sleep while he was on tour in Germany. The anesthesiologist would "[[Depressant|take him down]]" at night and "[[Stimulant|bring him back up]]" in the morning during the [[HIStory World Tour]] of 1996 and 1997.<ref name=DukeJuly8>{{cite news |last1=Duke |first1=Alan |last2=Ahmed |first2=Saeed |url=http://www.cnn.com/2009/SHOWBIZ/Music/07/09/jackson.wrap/index.html#cnnSTCVideo |title=More associates link Jackson to prescription drugs |agency=CNN |date=July 8, 2009 |access-date=July 9, 2009 |archive-date=March 4, 2016 |archive-url=https://web.archive.org/web/20160304060913/http://www.cnn.com/2009/SHOWBIZ/Music/07/09/jackson.wrap/index.html#cnnSTCVideo |url-status=live }}</ref>